Implementation of supportive care and best supportive care interventions in clinical trials enrolling patients with cancer
نویسندگان
چکیده
منابع مشابه
Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer.
BACKGROUND The extent to which chemotherapy may relieve tumour-related symptoms, improve quality of life and prolong survival in patients with gastric cancer is not known in spite of the extensive use of this treatment modality. The aim of this study was to estimate any gain in the quantity and quality of life produced by chemotherapy in these patients. PATIENTS AND METHODS Between January 19...
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BACKGROUND The use of chemotherapy has been proposed to increase the effectiveness of best supportive care (BSC) in patients with non-small cell lung cancer (NSCLC). Previous trials reported inconsistent findings regarding the efficacy and safety of chemotherapy on overall survival (OS) and treatment-related mortality. We performed a systematic review and meta-analysis to evaluate the effects o...
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OBJECTIVE To review recent findings on the utilization of massage by cancer patients, including evidence of effects in supportive and palliative cancer care, current understanding of safety considerations and adaptations needed, education of professional and family caregivers to provide this form of support, and guidelines for oncology nurses in referring patients. DATA SOURCES Journal articl...
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Dose and schedule are important factors in the therapy of cancer. Animal model and clinical data show that there is a significant correlation between dose-intensity and survival; moreover, the shortening of interval between chemotherapy cycles prevents from tumor regrowth and maximize the effect of chemotherapy on cancer cells (Gregory SA, Trumper L, 2005). Most of anti-cancer drugs are non-sel...
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In developed countries the survival rate of children with cancer exceeds 75%. Optimal supportive care is necessary to deliver the burdensome treatment protocols. As the intensity of primary treatment has escalated, so have the side effects like myelosuppression and infection. Children who receive aggressive chemotherapy have an approximately 40% chance of experiencing a febrile episode during n...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2015
ISSN: 0923-7534
DOI: 10.1093/annonc/mdv207